Founded in 1985, this company, based in Cirencester in Gloucestershire, manufactures cutting-edge orthopaedic implants and develops technologies to help provide customised treatments. A focus on pre-surgical diagnostics, as well as its 11 offices worldwide, helped overseas sales hit £97.9m in 2017. In June, chief executive Stefano Alfonsi, 54, oversaw the sale of the business to private equity firm Permira for an undisclosed sum.
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